Article on "TiO2 genotoxicity: An update of the results published over the last six years" Carriere, M., Arnal, M. E., & Douki, T. (2020).

Abstract:

TiO2 particles are broadly used in daily products, including cosmetics for their UV-absorbing property, food for their white colouring property, water and air purification systems, self-cleaning surfaces and photoconversion electrical devices for their photocatalytic properties. The toxicity of TiO2 nano- and microparticles has been studied for decades, and part of this investigation has been dedicated to the identification of their potential impact on DNA: their genotoxicity. This review summarizes data retrieved from their genotoxicity testing during the past 6 years, encompassing both in vitro and in vivo studies, mostly performed on lung and intestinal models. It shows that TiO2 particles, both nano- and micro-sized, produce genotoxic damage to a variety of cell types, even at low, realistic doses.

https://doi.org/10.1016/j.mrgentox.2020.503198